Complete Supplement Facts Master Table
The table below reproduces every active listed on the official Cognizil label. Unlike marketing pages that obfuscate proprietary mixtures, this reference desk identifies which quantities are openly declared and which remain grouped within the 15.47 mg blend.
| Active Component | Form / Source | Label Amount | Disclosure | Clinical Rating |
|---|---|---|---|---|
| 01. Chromium (as Chromium Picolinate) | High-Bioavailability Chromium Picolinate | 7 mcg (20% DV) | Disclosed | 84% Clinical Backing |
| 02. Maca Root Extract | Lepidium meyenii root extract (20:1 concentrate) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 82% Clinical Backing |
| 03. African Mango Seed Extract | Irvingia gabonensis seed extract (10:1 concentrate) | Proprietary Blend (undisclosed fraction of 15.47 mg; 10:1 equivalent) | Proprietary | 65% Clinical Backing |
| 04. Grape Seed Extract | Vitis vinifera seed extract (20:1 concentrate · OPCs) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 88% Clinical Backing |
| 05. Guarana Seed Extract | Paullinia cupana seed extract (20:1 concentrate) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 80% Clinical Backing |
| 06. Eleuthero Root Extract | Eleutherococcus senticosus root extract (20:1 concentrate) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 79% Clinical Backing |
| 07. Astragalus membranaceus Root Extract | Astragalus membranaceus root extract (20:1 concentrate) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 75% Clinical Backing |
| 08. Green Tea Leaf Extract | Camellia sinensis leaf extract (20:1 concentrate · EGCG) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 86% Clinical Backing |
| 09. Gymnema Sylvestre Leaf Extract | Gymnema sylvestre leaf extract (20:1 concentrate) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 68% Clinical Backing |
| 10. Coleus Forskohlii Root Extract | Coleus forskohlii root extract (20:1 concentrate · Forskolin) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 77% Clinical Backing |
| 11. Cayenne Pepper Fruit Extract | Capsicum annuum fruit extract (20:1 concentrate · Capsaicin) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 72% Clinical Backing |
| 12. Grapefruit Seed Extract | Citrus paradisi seed extract (20:1 concentrate · Bioflavonoids) | Proprietary Blend (undisclosed fraction of 15.47 mg; 20:1 equivalent) | Proprietary | 60% Clinical Backing |
| 13. Panax Ginseng Root Extract | Panax ginseng root extract (Standardized Ginsenosides) | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 91% Clinical Backing |
| 14. Raspberry Ketones | 4-(4-Hydroxyphenyl)butan-2-one (Phenolic Compound) | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 48% Clinical Backing |
| 15. L-Glutamine | Free-Form Amino Acid / Neurotransmitter Precursor | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 78% Clinical Backing |
| 16. L-Tyrosine | Free-Form Amino Acid / Catecholamine Precursor | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 87% Clinical Backing |
| 17. L-Arginine | USP Amino Acid / Nitric Oxide Substrate | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 83% Clinical Backing |
| 18. Beta Alanine | Beta-Amino Acid / Carnosine Precursor | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 70% Clinical Backing |
| 19. Monoammonium Glycyrrhizinate | Purified Licorice Glycyrrhizic Acid Derivative | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 58% Clinical Backing |
| 20. GABA (Gamma-Aminobutyric Acid) | Free-Form Inhibitory Neurotransmitter | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 81% Clinical Backing |
| 21. L-Tryptophan | Essential Amino Acid / Serotonin & Melatonin Precursor | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 85% Clinical Backing |
| 22. L-Carnitine HCl | Mitochondrial Fatty Acid Transporter | Proprietary Blend (undisclosed fraction of 15.47 mg) | Proprietary | 84% Clinical Backing |
Three Ingredients We Would Discount, and Why
Radical transparency requires objective critique. While Cognizil incorporates premier nootropics like Panax Ginseng, L-Tyrosine, and Grape Seed OPCs, three components carry weaker clinical justification in this specific concentration:
1. Raspberry Ketones (Clinical Score: 48%)
Raspberry ketones are popular in commercial weight loss supplements due to rodent metabolic studies. However, peer-reviewed double-blind human clinical trials demonstrating direct enhancement of human working memory, acetylcholine transmission, or cerebral microvascular perfusion are virtually absent. Its presence appears primarily cosmetic.
2. Monoammonium Glycyrrhizinate (Clinical Score: 58%)
Derived from licorice root, glycyrrhizinate acts primarily as a functional excipient and mucosal soothing agent in liquid tinctures. While harmless at micro-doses, buyers should recognize it as a formula stabilizer rather than an active cognitive optimizer.
3. African Mango Seed Extract (Clinical Score: 65%)
Irvingia gabonensis has demonstrated benefits for glycemic and lipid parameters in metabolic trials. However, its cognitive benefits operate indirectly through metabolic balance rather than acute neurotransmitter modulation.
Interactions Worth Clearing First
Although Cognizil is formulated with generally recognized safe (GRAS) dietary ingredients, specific metabolic and vascular pathways necessitate medical clearance before use:
- Antidiabetic Medications & Insulin: Chromium picolinate (7 mcg) and Gymnema sylvestre support insulin sensitivity and peripheral glucose uptake. Patients taking prescription insulin or metformin should monitor fasting glucose closely to prevent unexpected hypoglycemia.
- Antihypertensives & Vasodilators: L-Arginine, Capsicum fruit extract, and Grape Seed extract stimulate nitric oxide synthesis and vascular endothelial relaxation. If you take prescription blood pressure medications or organic nitrates, discuss this synergistic effect with your cardiologist.
- Antidepressants (SSRIs & MAOIs): L-Tryptophan serves as a direct biological precursor for central serotonin synthesis. Combining exogenous tryptophan with prescription selective serotonin reuptake inhibitors requires direct physician supervision.